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【招聘】南方医科大学皮肤病医院杨斌团队中美联合梅毒研究项目招收博士后两名 
 

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0pt">职位描述

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minor-latin;mso-font-kerning:0pt">Position/

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minor-latin;mso-font-kerning:0pt">职位:Postdoctoral

Researcher/博士后

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minor-latin;mso-font-kerning:0pt">NumberofPositions/

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0pt">招聘人数:2

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minor-latin;mso-font-kerning:0pt">Specialization/

11.0pt;font-family:宋体;mso-ascii-theme-font:minor-fareast;mso-fareast-theme-font:

minor-fareast;mso-hansi-theme-font:minor-fareast;mso-bidi-font-family:Calibri;

mso-bidi-theme-font:minor-latin;mso-font-kerning:0pt">专业要求:Pathogenic

Microbiology,MolecularBiology,StructuralBiology,etc./病原微生物学,分子生物学,结构生物学等

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minor-latin;mso-font-kerning:0pt">MinimumEducationalQualification/

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0pt">最低学历: Ph.D./博士

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minor-latin;mso-font-kerning:0pt">WorkExperience/

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">工作年限:Nospecificrequirement,candidateswith

experiencestudyingintheUnitedStatesarepreferred/经验不限,有留学经历者优先

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minor-latin;mso-font-kerning:0pt">ProfessionalTitleRequirements/

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">职称要求Notspecified/不限

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minor-latin;mso-font-kerning:0pt"> 

InternationalExchange/跨国交流

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line-height:18.35pt;mso-pagination:widow-orphan">

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0pt">Duringthestationperiod,youcanconductresearchprojectsatthe

SpirocheteResearchLaboratoriesoftheUniversityofConnecticut,Connecticut

Children’s-DivisionofInfectiousDiseases,andUConnHealth-Departmentsof

PediatricsandMedicine,undertheguidanceofProf.JustinRadolf.

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line-height:18.35pt;mso-pagination:widow-orphan">在站期间可前往美国康涅狄格大学SpirocheteResearchLaboratoriesConnecticutChildren’s-Division

ofInfectiousDiseases&UConnHealth-DepartmentsofPediatricsand

Medicine实验室在Prof.JustinRadolf指导下进行课题研究。

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0pt"> 

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0pt">JobResponsibilities/

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minor-latin;mso-font-kerning:0pt">岗位职责

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0pt">

line-height:18.0pt;mso-pagination:widow-orphan">

mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:minor-fareast;

mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">ParticipateinthecollaborativeprojectbetweentheNationalInstitutes

ofHealth(NIH)andChina,titled"Globalsequenceandsurfaceantigenic

diversityofTreponemapallidumoutermembraneproteins"

(UCHC7-122226512).Specifically,conductresearchonthedevelopmentof

nanovaccinesbycombiningsingle-cellomicssequencingtechnologiesand

bio-tracingtechniquestoscreenforsyphilisdiseaseprogressionbiomarkers

andprotectiveantibodies.

line-height:18.0pt;mso-pagination:widow-orphan">

font-family:宋体;mso-ascii-theme-font:minor-fareast;mso-fareast-theme-font:minor-fareast;

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minor-latin;mso-font-kerning:0pt">参与美国国立卫生研究院(NIH)与中国的合作项目“梅毒螺旋体外膜蛋白全球测序和表面抗原多样”(UCHC7-122226512)。具体开展结合单细胞等组学测序技术和生物示踪技术,筛选梅毒疾病进展生物标记物及保护性抗体用于纳米疫苗的开发研究。

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Wingdings;mso-bidi-font-family:Wingdings;mso-font-kerning:0pt">Ø 

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">Familiaritywithclinicalaspectsofsyphilisanditsimmunopathogenic

mechanisms,aswellasfoundationalexperimentsandanimalexperimentsrelated

tosyphilis./

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">熟悉梅毒临床相关内容及其免疫学发病机制,梅毒相关基础实验和动物实验;

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Wingdings;mso-bidi-font-family:Wingdings;mso-font-kerning:0pt">Ø 

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">ProkaryoticexpressionandpurificationofkeyECL(extracellularloop)of

Treponemapallidumcandidateproteins. / 

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">梅毒螺旋体候选蛋白关键ECL的原核表达,纯化;

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Wingdings;mso-bidi-font-family:Wingdings;mso-font-kerning:0pt">Ø 

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">DetectionofthereactionbetweenkeyECLandantibodiesfromdifferent

patientsera./ 

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minor-latin;mso-font-kerning:0pt">关键ECL与不同病人血清抗体的反应检测;

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Wingdings;mso-bidi-font-family:Wingdings;mso-font-kerning:0pt">Ø 

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">UsebioinformaticstoolstoanalyzethegenomicpolymorphismofTreponema

pallidum,focusingonthevariationofoutermembraneproteins./ 

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">利用生物信息学工具解析梅毒螺旋体基因组多态性,聚焦螺旋体外膜蛋白的变异;

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mso-pagination:widow-orphan;mso-list:l1level1lfo2">

Wingdings;mso-bidi-font-family:Wingdings;mso-font-kerning:0pt">Ø 

mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:minor-fareast;

mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">PreparationofmonoclonalantibodiesfromBCR(Bcellreceptor)sequences

ofskinlesions. /

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mso-hansi-theme-font:minor-fareast;mso-bidi-font-family:Calibri;mso-bidi-theme-font:

minor-latin;mso-font-kerning:0pt">从皮损BCR序列制备单克隆抗体;

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Wingdings;mso-bidi-font-family:Wingdings;mso-font-kerning:0pt">Ø 

mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:minor-fareast;

mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">Screenandvalidateantibodiesobtainedfromtheexistingsyphilisprotein

library.Usetheobtainedantibodiestoscreen,identify,andanalyzeunknown

syphilisproteins./ 

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mso-hansi-theme-font:minor-fareast;mso-bidi-font-family:Calibri;mso-bidi-theme-font:

minor-latin;mso-font-kerning:0pt">用现有的梅毒蛋白库,筛选和验证得到的抗体,并用得到的抗体,筛选和鉴定和解析未知梅毒蛋白;

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Wingdings;mso-bidi-font-family:Wingdings;mso-font-kerning:0pt">Ø 

mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:minor-fareast;

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0pt">Otherresearchrelatedtosyphilis./

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minor-latin;mso-font-kerning:0pt">其他梅毒相关的研究。

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0pt"> 

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">CompensationandBenefits/

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minor-latin;mso-font-kerning:0pt">薪酬与福利待遇

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0pt">

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.4pt;mso-font-kerning:0pt">Competitivesalaryandresearchteamconditionswill

beprovidedontheresearchplatform.Enjoysocialinsurance,housingfund,and

relevantbenefitsfromthehospital,includingaccommodation.Afterentering

thestation,thereisapostdoctoralstartupfee,andduringthestation

period,thereissupportingfundingfornationalandprovincialprojects.

Outstandingperformersmayhavetheopportunitytostayonattheinstitute

afterleavingthestation,withresettlementfeesandestablishmentinthecareer

system.

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font-family:宋体;mso-ascii-theme-font:minor-fareast;mso-fareast-theme-font:minor-fareast;

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">研究平台将提供具有竞争力的薪酬待遇以及科研团队条件。享受五险一金及医院的相关福利待遇,提供住宿。入站后院内有博后启动经费,在站期间立项的国家、省级课题院内有配套经费,表现优异者出站后可留院工作,享受相应待遇。

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0pt"> 

mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:minor-fareast;

mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">JobRequirements/

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mso-hansi-theme-font:minor-fareast;mso-bidi-font-family:Calibri;mso-bidi-theme-font:

minor-latin;mso-font-kerning:0pt">岗位要求

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0pt">

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">Ph.D.graduatein

relevantmajorssuchaspathogenicmicrobiology,molecularbiology,structural

biology,etc./

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;letter-spacing:

.4pt;mso-font-kerning:0pt">病原微生物学、分子生物学、结构生物学等相关专业背景博士毕业;

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0pt">

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font-family:宋体;mso-ascii-theme-font:minor-fareast;mso-fareast-theme-font:minor-fareast;

mso-hansi-theme-font:minor-fareast;mso-bidi-font-family:Calibri;mso-bidi-theme-font:

minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">Experienceinrecombinant

proteinexpressionusingexpressionsystemslikeEscherichiacoliandmammalian

cells,aswellasrelatedworkinexpressionsystemselection,purification,

antigen/antibodyproduction,andidentification.Experienceinthestudyof

bacterialoutermembraneproteinsispreferred./

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">Basicunderstandingof

bioinformatics./

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">Strongresearchliteracy,

abilitytoplanandexecuteexperiments,solveexperimentalproblems,and

analyzeresults./

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communication,coordination,andexpressionskills./

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专家简介

中方导师:杨斌

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minor-latin;letter-spacing:1.15pt;mso-font-kerning:0pt">二级主任医师、教授、博士研究生导师、博士后合作导师

国务院特殊津贴专家,南方医科大学皮肤病医院党委书记、院长,美国北卡罗莱纳大学客座教授,广东粤港皮肤科学研究联合实验室主任,国家药监局化妆品安全性评价重点实验室副主任。

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">从事皮肤病临床、教学、科研多年,期间曾在英国伦敦大学及美国华盛顿大学深造,临床及科研工作经验丰富。主要研究方向为免疫炎症性皮肤病、损容性皮肤病、梅毒研究。近年来带领团队重点聚焦增生性瘢痕成纤维细胞增殖调控、皮肤类器官以及梅毒潜伏感染免疫逃逸机制研究,同时与美国杜克大学、康涅狄格大学优秀科研团队合作,结合单细胞等组学测序技术和生物示踪技术,筛选梅毒疾病进展生物标记物及保护性抗体用于纳米疫苗的开发研究。先后主持国家自然科学基金国合重点项目、面上项目、NIH国际合作项目及省自然科学基金13项,获省级科技进步奖三项,实用新型专利四项,主编及参编著作12部。以第一作者或通讯作者发表学术论文130余篇,SCI收录110余篇,其中部分研究成果已发表在NatureCommunications、ProteinCell、JAMADermatology、JAAD、JAC、JID等高水平专业期刊上。目前已培养博士生7名,硕士生20余名,博士后6名,先后荣获“广东省医学领军人才”“全国先进工作者”“全国优秀中青年医师”“第二届广东医师”“广东优秀院长”“首届羊城名医”等称号。

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">Dr.YangBin,an

AssociateChiefPhysician,Professor,Ph.D.Supervisor,andPostdoctoral

CollaborativeSupervisor,isarecipientoftheStateCouncil'sSpecial

Allowance.ShecurrentlyservesasthePartySecretaryandDeanofthe

DermatologyHospitalatSouthernMedicalUniversity.Additionally,sheholdsa

positionasaVisitingProfessorattheUniversityofNorthCarolinainthe

UnitedStatesandservesastheDirectoroftheJointLaboratoryof

DermatologicalScienceResearchinGuangdong,HongKong.Dr.Yangisalsothe

DeputyDirectoroftheKeyLaboratoryforCosmeticSafetyEvaluationatthe

NationalMedicalProductsAdministration.

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">Withyearsofexperience

inclinicalpractice,teaching,andresearchindermatology,Dr.Yangpursued

furtherstudiesattheUniversityofLondonintheUKandWashingtonUniversity

intheUS,accumulatingextensiveclinicalandresearchexperience.Her primary

researchinterestsincludeimmunoinflammatoryskindiseases,disfiguringskin

diseasesandsyphilis.Inrecentyears,shehasledateamfocusingonthe

regulationofscarfibroblastproliferation,thestudyofskin-likeorgans,and

theimmuneevasionmechanismoflatentsyphilisinfection.Collaboratingwith

excellentresearchteamsfromDukeUniversityandtheUniversityofConnecticut

intheUnitedStates,Dr.Yangemployssingle-cellomicssequencing

technologiesandbio-tracingtechniquestoidentifybiomarkersandprotective

antibodiesforthedevelopmentofnanovaccinesagainstsyphilis.

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">Dr.Yanghassuccessfully

lednumerousresearchprojectsfundedbynationalandprovincialgrants,

receivingrecognitionthroughawardsandpatents.Shehasauthoredor

co-authoredover120academicpapers,withmanypublishedinprestigious

journalssuchasNatureCommunications,ProteinCell,JAMADermatology,and

others.Dr.Yanghasalsosupervisedthetrainingofsevendoctoralstudents,

over20master'sstudents,andsixpostdoctoralresearchers,earning

her titlesandhonorssuchas"LeadingMedicalTalentinGuangdong

Province,""NationalAdvancedWorker,""National

OutstandingYoungPhysician,"andothers.

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1.15pt;mso-font-kerning:0pt">美方导师:JustinD.Radolf

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">康涅狄格大学医学、儿科、分子生物学与生物物理学、遗传学与基因组科学以及免疫学教授

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">医学科研部主任

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">康涅狄格州儿童医学中心高级科学顾问

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">Justin

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.4pt;mso-font-kerning:0pt">教授在梅毒基础研究尤其是螺旋媒体研究有非常丰富的经验和深厚的研究基础,1999年至今,他在梅毒领域的研究一直受到美国NIH的资助,他共主持申请了42项美国国立卫生院等项目,对梅毒螺旋体进行深入的研究,获资助金额超过3000万美元,目前有一项梅毒的在研项目(NIH项目);申请获得一项梅毒螺旋体相关专利;共发表包括梅毒研究在内的传染病相关研究文章204篇(其中关于梅毒的一项研究发表在医学领域顶刊《新英格兰医学杂志》上),应邀参加125场梅毒螺旋体相关研究的会议并发言;参与编写三本传染病相关专著;为两本梅毒相关的专著撰写章节:《TreponemaandBrachyspira,HumanHost-AssociatedSpirochetes》,《Treponemapallidum(Syphilis)》

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">Co-PIProfessorJustinD.

Radolf

Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:0pt">

minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">ProfessorofMedicine,

Pediatrics,MolecularBiologyandBiophysics,GeneticsandGenomeSciences,and

Immunology

Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:0pt">

minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">DirectorofResearch,

DepartmentofMedicine

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">SeniorScientific

Advisor,ConnecticutChildren’sMedicalCenter

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minor-latin;letter-spacing:.4pt;mso-font-kerning:0pt">ProfessorJustinhas

extensiveexperienceandaprofoundresearchfoundationinthefieldof

syphilisbasicresearch,especiallyinthestudyofspirochetes.Since1999,

hisresearchinthefieldofsyphilishasbeencontinuouslyfundedbytheU.S.

NIH.Hehasjointlyappliedfor42projectsfromtheU.S.NationalInstitutes

ofHealthandotherinstitutions,conductingin-depthresearchonsyphilis

spirochetes,withfundingtotalingover30millionU.S.dollars.Currently,he

hasanongoingsyphilisproject(NIHproject)andhasappliedforapatent

relatedtosyphilisspirochetes.Hehaspublishedover200researcharticleson

infectiousdiseases,includingsyphilisresearch,withonesyphilis-related

studypublishedintheprestigiousmedicaljournal"TheNewEngland

JournalofMedicine."Additionally,hehasbeeninvitedtospeakat125

conferencesonsyphilisspirochetes.Hehasalsocontributedchapterstotwo

syphilis-relatedmonographs:"TreponemaandBrachyspira,HumanHost-Associated

Spirochetes"and"Treponemapallidum(Syphilis)."

minor-latin;mso-font-kerning:0pt">

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text-indent:-1.0pt;mso-char-indent-count:-.09;mso-pagination:widow-orphan">

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">Please sendyourresumeandcoverletterto:yangbin101@hotmail.com

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">请将您的简历和求职信发送至邮箱:yangbin101@hotmail.com

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mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-font-kerning:

0pt">团队长期欢迎其他研究方向的有志之士加入,不限名额!

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南方医科大学皮肤病医院

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